《合金装备4》游戏原声于5月28日在日本地区提前发售，价格为3045日元。《合金装备4》游戏原声将包含游戏中共47首音乐。

Disc 1
01 Old Snake
02 Love Theme
03 Gekko
04 Haven Troopers
05 BB Corps
06 Drebin 893
07 Vista Mansion
08 Laughing Octopus
09 Breakthrough
10 Endless Pain
11 White Blood
12 Call Me Hal
13 Midnight Shadow
14 Paradise Lost
15 Great Escape
16 Desperate Chase
17 Raging Raven
18 Confrontation
19 Mobs Alive
20 Violent Ceasefire

Disc 2
01 Next-Gen Control
02 Crying Wolf
03 One More Reboot
04 Sin
05 Atonement
06 Infinite Loop
07 Everything Ends
08 At Dawn
09 Screaming Mantis
10 Guns of the Patriots
11 No Place to Hide
12 Sorrow
13 Full Circle
14 Everything Begins
15 Father & Son
16 Metal Gear Saga
17 Here's To You
18 War Zone
19 A Rebellion Rests
20 The Hunter
21 The Hunted
22 Forced Hand
23 Under Curfew
24 Unmanned Army
25 Cold Memories
26 For Liberty
27 Surrounde

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